Rare Case of Acquired Haemophilia and Lupus Anticoagulant
نویسندگان
چکیده
منابع مشابه
Lupus anticoagulant, anticardiolipin antibodies, and human immunodeficiency virus in haemophilia.
The prevalence of lupus anticoagulant, using the dilute Russell's viper venom time (DRVT), was determined in 22 patients with mild to severe haemophilia A to see if there was any association with the presence of viral disease. Twelve haemophiliacs (58%) were lupus anticoagulant positive, with a mean patient:control ratio of 1.24 (range 1.15-1.52, normal range 0.84-1.06 which partially corrected...
متن کامل[Acquired haemophilia in a patient with systemic lupus erythematosus].
INTRODUCTION In patients with lupus, the most common acquired circulating anticoagulant is antiprothrombinase which is responsible for thrombosis. The presence of antibodies directed against factor VIII is rarely found in systemic lupus erythematosus. A case of acquired haemophilia in a patient with lupus is reported. CASE REPORT A 30 year-old woman with systemic lupus erythematosus developed...
متن کاملAcquired haemophilia A: a case report.
A 40 year old male patient was admitted in ICU of Hosmat Hospital & Research Centre, Bangalore. There was a history of fall from a motor bicycle. There was a marked swelling over the lower twothird of his right thigh. X-ray of the thigh revealed no fracture. There was a massive muscle hematoma. Hematoma was gradually increasing in size giving indication of persistence of bleeding. The patient a...
متن کامل[Acquired haemophilia].
Acquired haemophilia (AH) is a severe bleeding diathesis that affects both males and females. It is caused by suddenly appearing autoantibodies that interfere with coagulation factor VIII (FVIII) activity. Although some conditions such as autoimmune diseases, cancer and puerperium seem likely to induce AH, in more than half of the observed cases autoantibodies to FVIII are idiopathic. The clini...
متن کاملA case series of acquired haemophilia in a Malaysian hospital: unpredictably rare medical emergency
Acquired haemophilia (AH) is a rare bleeding disorder characterized by the presence of acquired inhibitors against Factor VIII causing disruption of coagulation cascade. It has no known genetic inheritance, and diagnosis remains a challenge. The peculiar presentations are later age of onset as acute pain in weight-bearing joints and spontaneous muscle haematoma with isolated prolonged activated...
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ژورنال
عنوان ژورنال: Indian Journal of Hematology and Blood Transfusion
سال: 2012
ISSN: 0971-4502,0974-0449
DOI: 10.1007/s12288-012-0204-5